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Blood Test for Kidney Stones - What to Expect, Report Value

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Medically Reviewed by Dr. Aman Priya Khanna
Written by Charu Shrivastava, last updated on 29 September 2023| min read
Blood Test for Kidney Stones - What to Expect, Report Value

Quick Summary

  • Kidney stones are a common and painful condition that can affect anyone at any age.
  • A blood test for kidney stones can provide valuable information about your kidney function and help your doctor determine the best course of treatment for you.
  • If you suspect that you may have kidney stones, talk to your doctor about getting a blood test.

Kidney stones are a common and painful condition that can affect anyone at any age. If you suspect that you may have kidney stones, your doctor may recommend a blood test to help diagnose and monitor the condition.

A blood test for kidney stones can provide valuable information about your kidney function and help your doctor determine the best course of treatment for you.

In this blog, you will learn how to test for kidney stones and what can you expect during the testing process. So, keep reading!

What are Kidney Stones?

Kidney stones are one of the most painful and common urological conditions. This condition is caused by the accumulation of salt and mineral deposits in the kidneys, which can then travel down the urinary tract, causing blockages. In India, around 12% of the population is suffering from kidney stone disease (KSD).

Kidney stones can occur by a variety of factors, including diet, genetics, insufficient water intake, and certain medical conditions (gout, high blood pressure, diabetes, etc.). Irrespective of the cause, their symptoms can range from mild discomfort to excruciating pain.

These irregular-shaped solid crystals can range in size from a grain of sand to a golf ball. You may not even realise that you have kidney stones if their size is too small. However, even small stones can cause extreme pain if they get stuck in the urinary tract.

If a large kidney stone gets trapped in your urinary tract, it can cause bleeding and make it difficult for you to pass urine. In this case, you need surgery to remove the stones.

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How to Test for Kidney Stones?

Diagnosing kidney stones usually involves a detailed medical history taking, followed by a physical examination, laboratory tests, and imaging tests. These tests are as follows.

  1. Medical history: The doctor first records a complete medical history. They will gather information about current symptoms, medical conditions, previous kidney stone events, dietary history, medications, and family history.
  2. Physical examination: The doctor will perform a physical examination to evaluate the signs of kidney stones, including pain in the lower back, flank (sides), or groin.
  3. Blood tests for kidney stones: Blood tests are one of the key diagnostic tools used by doctors to diagnose kidney stones. They help to determine high levels of a particular mineral in the blood that is causing kidney stones.
    The doctor will test your blood for calcium, uric acid, and phosphorus. Several different blood tests for kidney stones are: 
    1. Basic metabolic panel (BMP): A BMP measures the levels of several different substances in the blood, including electrolytes (sodium, potassium, chloride, bicarbonate), glucose, calcium, blood urea nitrogen (BUN), and creatinine.
      Abnormal levels of these substances can indicate an underlying medical condition that may be contributing to the formation of kidney stones.
    2. C-reactive protein (CRP): CRP is a protein that is produced in response to inflammation in the body. Elevated levels of CRP can indicate the presence of an infection, which may be present in kidney stones.
  4. Urine tests: Urine tests can help doctors identify any underlying medical conditions that may be contributing to the formation of kidney stones.
    For example, a urinalysis can help doctors identify the presence of blood in the urine (a sign of a kidney stone) and minerals that are causing kidney stones (excess calcium).
    The presence of bacteria and white blood cells in the urine may indicate a urinary tract infection.
  5. Imaging tests: Even though all the above-mentioned tests are essential, a kidney stone can only be confirmed by radiological testing. In most cases, a simple Kidney-ureter-bladder (KUB) x-ray will be suitable to detect a kidney stone.
    However, if your doctor needs more details, they may suggest a computed tomography (CT) scan or intravenous pyelogram (IVP).
    1. KUB test for kidney stones: This helps to determine the location and the size of the stone. Often, a KUB x-ray is obtained by the doctors to determine if the kidney stone is suitable for shock wave treatment.
    2. Intravenous pyelogram (IVP): IVP is a special type of X-ray in which a dye is injected to obtain an X-ray of the urinary system.
    3. CT scan: CT scans use a combination of computer technology and X-ray to create images of the urinary tract.
      It helps to determine the location and size of the kidney stone, conditions that may have caused the kidney stone formation, and if the stone is blocking the urinary tract.

Importance of Blood Tests for Kidney Stone

Blood tests are an essential tool for diagnosing and monitoring kidney stones, as well as assessing overall kidney function. According to the American Kidney Fund, blood tests help

  1. Identify underlying causes of kidney stones, such as high levels of calcium, uric acid, or other substances in the blood.
  2. Assess kidney function. Creatinine is a waste product produced by the muscles and excreted by the kidneys.
    Elevated levels of creatinine in the blood can be a sign of kidney damage or dysfunction, which can occur as a result of kidney stones.
  3. Monitor the effectiveness of treatment for kidney stones.
  4. Detect signs of infection. e.g, elevated white blood cells.

Overall, blood tests are just one tool that doctors use for diagnosing kidney stones. Other tests like urinalysis, imaging tests, etc., are often used in conjunction with blood tests to provide comprehensive information and accurate diagnosis.

Types of Blood Tests for Kidney Stones

There are several types of blood tests that can be used to diagnose and monitor kidney stones. These tests measure levels of different substances in the blood that can help identify the underlying causes of kidney stones and assess kidney function.

Here are some of the most common blood tests used for kidney stones:

  1. Complete Blood Count (CBC): This test measures levels of red blood cells, white blood cells, and platelets in the blood. While a CBC is not specific to kidney stones, it can help identify infections or inflammation that may be contributing to the condition.
  2. Electrolyte Panel: This test measures levels of sodium, potassium, calcium, and other electrolytes in the blood. High levels of calcium or uric acid can contribute to the formation of kidney stones, so this test can help identify these underlying causes.
  3. Creatinine and Blood Urea Nitrogen (BUN): These tests measure levels of waste products in the blood that are normally excreted by the kidneys.
    High levels of creatinine or BUN can be a sign of kidney damage or dysfunction, which can occur as a result of kidney stones.
  4. Parathyroid Hormone (PTH) Test: This test measures levels of PTH in the blood, which can help identify hyperparathyroidism, a condition in which the parathyroid glands produce too much PTH.
    This can lead to high levels of calcium in the blood, which can contribute to the formation of kidney stones.

Procedure for Blood Test for Kidney Stone

A blood test for kidney stone is a simple and routine procedure that involves the following steps:

  1. You will be told to sit on the chair and the healthcare provider (phlebotomist) will check your arms for an easily accessible vein in your elbow.
  2. They will clean and disinfect the area after locating the vein.
  3. A small needle will be inserted into the vein to withdraw blood.
  4. The blood is collected in a test tube and the provider will remove the needle as they have sufficient blood to test.
  5. They will place a gauze or a cotton ball on the site to stop the bleeding.
  6. The provider will then send the blood sample to a laboratory for testing.

Depending on the specific tests that your doctor has ordered, the results may be available within a few hours or several days. The entire procedure for the blood test usually takes less than 5 minutes.

Interpretation of the Blood Test for Kidney Stone

Interpreting the results of a blood test for kidney stones requires the expertise of a healthcare professional, as the results can vary depending on the specific tests that were performed and the individual patient's medical history.

Here are some general guidelines for interpreting the most common blood tests used for kidney stones:

  1. Complete Blood Count (CBC): A CBC measures levels of red blood cells, white blood cells, and platelets in the blood. 
    1. The normal ranges of the contents of CBC are as follows:
      1. RBC count: Female: 4.2 to 5.4 million cells/mcL; Male: 4.7 to 6.1 million cells/mcL
      2. WBC count: 4,500 to 10,000 cells/mcL
      3. Haemoglobin: Female: 12.1 to 15.1 gm/dL; Male: 13.8 to 17.2 gm/dL
      4. Haematocrit: Female: 36.1 to 44.3%; Male: 40.7 to 50.3%
      5. Red blood cell indices: 
        1. Mean corpuscular volume (MCV): 80 to 95 femtoliter
        2. Mean corpuscular haemoglobin (MCH): 27 to 31 pg/cell
        3. Mean corpuscular haemoglobin concentration (MCHC): 32 to 36 gm/dL
      6. Platelet count: 150,000 to 4,50,000/dL
      7. CRP level: Less than 0.9 mg/dL
      8. Glucose level: Fasting blood glucose level: 70-99 mg/dL
    2. Abnormal results may indicate an infection or inflammation, which can contribute to the formation of kidney stones.
  2. Electrolyte Panel: An electrolyte panel measures levels of sodium, potassium, calcium, and other electrolytes in the blood. 
    1. The normal ranges of the electrolyte panel are as follows:
      1. Potassium: 3.5 to 5 mmol/L
      2. Sodium: 136 to 145 mmol/L
      3. Chloride: 96 to 106 mmol/L
      4. Bicarbonate level: 22 to 32 mmol/L
    2. High levels of calcium or uric acid may indicate an underlying cause of kidney stones, such as hyperparathyroidism or gout.
  3. Creatinine and Blood Urea Nitrogen (BUN): Creatinine and BUN tests measure levels of waste products in the blood that are normally excreted by the kidneys. 
    1. The normal ranges:
      1. Creatinine level: Females: 0.5 to 1.1 mg/dL; Males: 0.7 to 1.3 mg/dL.
      2. BUN level: Female: 6 to 21 mg/dL; Male: 8 to 24 mg/dL; Children (1-17 years): 7 to 20 mg/dL
    2. High levels may indicate kidney damage or dysfunction, which can occur as a result of kidney stones.
  4. Parathyroid Hormone (PTH) Test: A PTH test measures levels of PTH in the blood. 
    1. The normal range of this test is 10 to 55 picograms per millilitre (pg/mL).
    2. High levels may indicate hyperparathyroidism, which can contribute to the formation of kidney stones.

Factors Affecting the Blood Test for Kidney Stone Results

Several factors can affect the results of blood tests used to diagnose kidney stones. These include:

  1. Medications: Certain medications can affect the levels of substances in the blood that are measured in kidney stone blood tests.
    For example, diuretics can increase urine output and decrease blood volume, which can affect electrolyte levels.
    It is important to inform your healthcare provider of any medications you are taking before undergoing blood tests for kidney stones.
  2. Dehydration: Dehydration can affect the concentration of substances in the blood and urine, which can affect the results of kidney stone blood tests. It is important to stay well-hydrated before undergoing blood tests for kidney stones.
  3. Time of day: Some substances, such as calcium and PTH, may have higher levels in the blood in the morning compared to later in the day. It is important to follow your healthcare provider's instructions regarding when to undergo blood tests for kidney stones.
  4. Medical conditions: Certain medical conditions, such as hyperparathyroidism or chronic kidney disease, can affect the levels of substances in the blood that are measured in kidney stone blood tests.
  5. Dietary factors: Certain foods, such as those high in calcium or oxalate, can affect the levels of these substances in the blood and urine. It is important to follow any dietary instructions provided by your healthcare provider before undergoing blood tests for kidney stones.

Next Steps after a Blood Test for Kidney Stone

The next steps after a blood test for kidney stones depend on the results and the individual patient's medical history. Here are some general guidelines:

  1. Normal Results: If the results of the blood test are normal, further testing may not be necessary. Your healthcare provider may recommend lifestyle changes, such as drinking more water and avoiding certain foods that can contribute to kidney stone formation.
  2. Abnormal Results: If the results of the blood test are abnormal, your healthcare provider may recommend further testing to determine the cause of the abnormalities.
    This may include imaging tests, such as an ultrasound or CT scan, or additional blood and urine tests.
  3. Referral to a Specialist: If the abnormalities are severe or the cause is unclear, your healthcare provider may refer you to a specialist, such as a nephrologist or a urologist, for further evaluation and treatment.
  4. Treatment: Treatment for kidney stones depends on the size and location of the stones, as well as the individual patient's medical history. Treatment options may include medications to help pass the stones, procedures to break up or remove the stones, or surgery in rare cases.

Takeaway

Kidney stones are a painful and common urological condition. Blood tests for kidney stones include blood and urine tests as well as imaging tests. By working with your doctor and undergoing the necessary tests, you can help diagnose kidney stones and develop an effective treatment plan.

If you still have any questions related to blood tests for kidney stones, feel free to contact our personal care team at HexaHealth. We are always happy to help! Our team will guide you thoroughly and solve all your queries. You can also visit our website HexaHealth if you want to learn more about blood tests for kidney stones or other related information.

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Frequently Asked Questions

Yes, your doctor may ask you for a blood test to confirm kidney stones. The blood test help to determine high levels of a particular mineral in the blood that is causing kidney stones such as uric acid, calcium, and phosphorus.
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For kidney stones, your doctor will ask for a detailed medical history, perform a physical examination, and ask for laboratory (urinalysis and blood tests for kidney stones) and imaging tests (X-rays, ultrasounds, and CT scans).
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Blood tests, urinalysis, and imaging tests are the most reliable and accurate lab tests to confirm kidney stones. However, consult your doctor.
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KUB test for kidney stones helps to determine the location and the size of the stone. Often, this test helps the doctors determine if the kidney stone is suitable for shock wave treatment.
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The dye test for kidney stones is an intravenous pyelogram (IVP). IVP is a special type of X-ray in which a dye is injected to obtain an X-ray of the urinary system to check for blockages.
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For kidney stones in children, the doctor will ask for medical history, perform a physical examination, and ask for imaging tests (X-rays, ultrasounds, and CT scans) and laboratory tests (blood tests and urinalysis).
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For kidney stones, the doctor will ask for the patient’s medical history, physical examination (to confirm signs of kidney stone), perform blood tests, urinalysis, and imaging tests. Based on the result, the doctor will suggest treatment accordingly.
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For kidney stones, you can look for signs like pain in the lower back or side of the body, blood in the urine, painful urination, urine that looks cloudy or smells bad, and fever and chills (in cases of infection). If you notice any of these signs, contact your doctor.
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Urinalysis can be used to detect kidney stones in the urine. The urine sample is examined for the presence of blood in the urine (a sign of a kidney stone), minerals that are causing kidney stones (excess calcium), and infection.
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The fastest way to diagnose kidney stones is by X-rays, ultrasounds, and CT scans. However, consult your doctor if you notice signs or symptoms of kidney stones.
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A complete blood count (CBC) is among the first tests done to check for kidney stones and to check if there is an infection associated with the stone.

The CBC test measures red blood cells (RBCs), white blood cells (WBCs), haemoglobin, haematocrit, mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC).

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Yes, blood tests help to determine kidney problems. In kidney stones, the blood test may aid to determine high levels of a particular mineral in the blood that is causing kidney stones. High creatinine levels can also point to complications occurring due to kidney stones.
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The cost of blood tests for kidney stones may vary in different cities in India. For example, the average cost of a blood test for a kidney stone in Mumbai is ₹ 928, whereas in Delhi it is ₹ 625.
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Yes, fasting is required for the blood test for kidney stones. You will be informed that you need to fast for at least eight hours before a blood test such as BMP.

Fasting might be recommended before a blood test for kidney stones to measure the levels of certain substances in the blood that can be affected by food intake. For example, calcium and uric acid levels in the blood can be influenced by what you eat, and fasting can help ensure more accurate results.

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It depends on the tests and the diagnostic centre. Some tests can provide results on the same day while some may take one or two days.
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In the blood test reports such as BMP, the reports provide the following details:

  1. The name of the blood test 
  2. The measurement or number of the blood test result
  3. The normal range for the test
  4. Information that shows if your results are abnormal (high or low) or normal.
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You must first consult your doctor after you receive your blood tests for kidney stones. They will take into consideration your medical history, current medication, and results, and will accordingly suggest further testing and treatment.
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Blood tests are an essential part of medical screening and testing. However, there are some minor risks to having blood tests. You may notice a bruise or slight tenderness at the site of the blood draw, which usually resolves in two to three days without any treatment.
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References

All the articles on HexaHealth are supported by verified medically-recognized sources such as; peer-reviewed academic research papers, research institutions, and medical journals. Our medical reviewers also check references of the articles to prioritize accuracy and relevance. Refer to our detailed editorial policy for more information.


  1. Uric acid stones: Causes, symptoms & treatment [Internet]. Cleveland Clinic. 2021.link
  2. Guha M, Banerjee H, Mitra P, Das M. The demographic diversity of food intake and prevalence of kidney stone diseases in the Indian continent. Foods. 2019;8(1):37.link
  3. Diagnosis of kidney stones - niddk [Internet]. National Institute of Diabetes and Digestive and Kidney Diseases. U.S. Department of Health and Human Services; 2017.link
  4. Goldfarb DS, Arowojolu O. Metabolic evaluation of first-time and recurrent stone formers. Urologic Clinics of North America. 2013.link
  5. Uric acid stones: Causes, symptoms & treatment [Internet]. Cleveland Clinic. 2021.link
  6. Kidney stones: Symptoms, causes, diagnosis, treatment & prevention. Cleveland Clinic. 2021.link
  7. Basic Metabolic Panel (BMP): What it is, procedure & results [Internet]. Cleveland Clinic. 2021.link
  8. Blood glucose (sugar) test: Levels & What They mean. Cleveland Clinic.link

Last Updated on: 29 September 2023

Disclaimer: The information provided here is for educational and learning purposes only. It doesn't cover every medical condition and might not be relevant to your personal situation. This information isn't medical advice, isn't meant for diagnosing any condition, and shouldn't replace talking to a certified medical or healthcare professional.

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Dr. Aman Priya Khanna

Dr. Aman Priya Khanna

MBBS, DNB General Surgery, Fellowship in Minimal Access Surgery, FIAGES

12 Years Experience

Dr Aman Priya Khanna is a well-known General Surgeon, Proctologist and Bariatric Surgeon currently associated with HealthFort Clinic, Health First Multispecialty Clinic in Delhi. He has 12 years of experience in General Surgery and worke...View More

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Charu Shrivastava

Charu Shrivastava

BSc. Biotechnology I MDU and MSc in Medical Biochemistry (HIMSR, Jamia Hamdard)

2 Years Experience

Skilled in SEO and passionate about creating informative and engaging medical content. Her proofreading and content writing for medical websites is impressive. She creates informative and engaging content that educ...View More

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